Publications

    2023

  1. Olaitan E Oladipupo, Meredith C Prescott, Emily R Blevins, Jessica L Gray, Colin G Cameron, Fengrui Qu, Nicholas A Ward, Abigail L Pierce, Elizabeth R Collinson, James Fletcher Hall, Seungjo Park, Yonghyun Kim, Sherri A McFarland, Igor Fedin, Elizabeth T Papish (2023) Ruthenium Complexes with Protic Ligands: Influence of the Position of OH Groups and π Expansion on Luminescence and Photocytotoxicity. International Journal of Molecular Sciences 24(6):5980.
  2. Yifei Sun, Sanjit Das, Spenser R Brown, Emily R Blevins, Fengrui Qu, Nicholas A Ward, Shawn Aiden Gregory, Chance M Boudreaux, Yonghyun Kim, Elizabeth T Papish (2023) Ruthenium pincer complexes for light activated toxicity: Lipophilic groups enhance toxicity. Journal of Inorganic Biochemistry 240:112110. PMID: 36596265.

  3. 2022

  4. Matthew DeBrunner, Skylar Elliott, Jordan Evans, Elizabeth Bury, Alexandra D. Avera, Yonghyun Kim, Amanda S. Koh (2022) Annealing for controlled galinstan oxide thin-film morphological and electromechanical properties. MRS Communications 12:1204-1211.
  5. Han-A Park, Spenser R Brown, Joseph Jansen, Tracie Dunn, Madison Scott, Nelli Mnatsakanyan, Elizabeth A. Jonas, Yonghyun Kim (2022) Fluid shear stress enhances proliferation of breast cancer cells via downregulation of the c-subunit of the F1Fo ATP synthase. Biochemical and Biophysical Research Communications 632:173-180. PMID: 36209586.
  6. Seungjo Park, Alexandra D Avera, Yonghyun Kim (2022) Biomanufacturing of glioblastoma organoids exhibiting hierarchical and spatially organized tumor microenvironment via transdifferentiation. Biotechnology and Bioengineering 119(11):3252-3274. PMID: 35869574.
  7. Pinaki S Nakod, Raghu Vamsi Kondapaneni, Brandon Edney, Yonghyun Kim, Shreyas S Rao (2022) The impact of temozolomide and lonafarnib on the stemness marker expression of glioblastoma cells in multicellular spheroids. Biotechnology Progress 38(5):e3284. PMID: 35768943.
  8. Spenser R Brown, Juliana C Bates, Alexandra D Avera, Yonghyun Kim (2022) Relationship between stemness, reactive oxygen species, and epithelial-to-mesenchymal transition in model circulating tumor cells. Cells Tissues Organs 211:312-323. PMID: 34077929.
  9. Olaitan E Oladipupo, Spenser R Brown, Robert W Lamb, Jessica L Gray, Colin G Cameron, Alexa R DeRegnaucourt, Nicholas A Ward, James Fletcher Hall, Yifei Xu, Courtney M Petersen, Fengrui Qu, Ambar B Shrestha, Matthew K Thompson, Marco Bonizzoni, Charles Edwin Webster, Sherri A McFarland, Yonghyun Kim, Elizabeth T Papish (2022) Light-responsive and protic ruthenium compounds bearing bathophenanthroline and dihydroxybipyridine ligands achieve nanomolar toxicity towards breast cancer cells. Photochemistry and Photobiology 98(1):102-116. PMID: 34411308.

  10. 2021

  11. Pinaki S Nakod, Yonghyun Kim, Shreyas S Rao (2021) The impact of astrocytes and endothelial cells on glioblastoma stemness marker expression in multicellular spheroids. Cellular and Molecular Bioengineering 14(6):639-651. PMID: 34900016.
  12. Jason E Bara, Yonghyun Kim, Ryan M Summers, C Heath Turner (2021) Chemical engineering at The University of Alabama. Chemical Engineering Education 55(2):70-75.
  13. Fengrui Qu, Robert W Lamb, Colin G Cameron, Seungjo Park, Olaitan Oladipupo, Jessica L Gray, Yifei Xu, Houston D Cole, Marco Bonizzoni, Yonghyun Kim, Sherri A McFarland, Charles Edwin Webster, Elizabeth T Papish (2021) Singlet oxygen formation vs photodissociation for light-responsive protic ruthenium anticancer compounds: The oxygenated substituent determines which pathway dominates. Inorganic Chemistry 60(4):2138-2148. PMID: 33534562.

  14. 2020

  15. Han-A Park, Spenser R Brown, Yonghyun Kim (2020) Cellular mechanisms of circulating tumor cells during breast cancer metastasis. International Journal of Molecular Sciences 21(14):5040. PMID: 32708855.
  16. Justin W Magrath, Wilson R Raney, Yonghyun Kim (2020) In vitro demonstration of salinomycin as a novel chemotherapeutic agent for the treatment of SOX2-positive glioblastoma cancer stem cells. Oncology Reports 44:777-785. PMID: 32627023.
  17. Seungjo Park, Jennifer A Sherwood, Rebecca M Hauser, Angelo J Antone, Brianna T Beswick, Farah D Lubin, Yuping Bao, Yonghyun Kim (2020) Surface effects of ultrasmall iron oxide nanoparticles on cellular uptake, proliferation, and multipotency of neural stem cells. ACS Applied Nano Materials 3(2):1542-1552.
  18. Pinaki S Nakod, Yonghyun Kim, Shreyas S Rao (2020) Three-dimensional biomimetic hyaluronic acid hydrogels to investigate glioblastoma stem cell behaviors. Biotechnology and Bioengineering 117(2):511-522. PMID: 31691953.
  19. Seungjo Park, Jessica L Gray, Sarah D Altman, Angela R Hairston, Brianna T Beswick, Yonghyun Kim, Elizabeth T Papish (2020) Cellular uptake of protic ruthenium complexes is influenced by pH dependent passive diffusion and energy dependent efflux. Journal of Inorganic Biochemistry 203:110922. PMID: 31775072.

  20. 2019

  21. Joline S Hartheimer, Seungjo Park, Shreyas S Rao, Yonghyun Kim (2019) Targeting hyaluronan interactions for glioblastoma stem cell therapy. Cancer Microenvironment 12(1):47-56. PMID: 31079324.
  22. Ursula L Triantafillu, Seungjo Park, Yonghyun Kim (2019) Fluid shear stress induces drug resistance to doxorubicin and paclitaxel in the breast cancer cell line MCF7. Advanced Therapeutics 2(3):1800112.
  23. Nara Shin, Hyeong-Geuk Kim, Hyo Jung Shin, Sena Kim, Hyeok Hee Kwon, Hyunjung Baek, Min-Hee Yi, Enji Zhang, Jwa-Jin Kim, Jinpyo Hong, Sun Yeul Lee, Wonhyung Lee, Ursula L Triantafillu, Cuk Seong Kim, Yonghyun Kim, Dong Woon Kim (2019) Uncoupled eNOS enhances p-Tau in chronic traumatic encephalopathy mouse model. Antioxidants & Redox Signaling 30(13):1601-1620. PMID: 30070145.

  24. 2018

  25. Grant M Landwehr, Andrew J Kristof, Sharif M Rahman, Jacob H Pettigrew, Rachael Coates, Joseph B Balhoff, Ursula L Triantafillu, Yonghyun Kim, Adam T Melvin (2018) Biophysical analysis of fluid shear stress induced cellular deformation in a microfluidic device. Biomicrofluidics 12(5):054109. PMID: 30364235.
  26. Fengrui Qu, Kristina P Martinez, Ashley M Arcidiacono, Seungjo Park, Matthias Zeller, Russel Schmehl, Jared J Paul, Yonghyun Kim, Elizabeth T Papish (2018) Sterically demanding methoxy and methyl groups in ruthenium complexes lead to enhanced quantum yields for blue light triggered photodissociation. Dalton Transactions 47(44):15685-15693. PMID: 30285013.
  27. Juhee Shin, Yuhua Yin, Hyewon Park, Seungjo Park, Ursula L Triantafillu, Yonghyun Kim, Sang Ryong Kim, Sun Yeul Lee, Do Kyung Kim, Jinpyo Hong, Dong Woon Kim (2018) p38 siRNA-encapsulated PLGA nanoparticles alleviate neuropathic pain behavior in rats by inhibiting microglia activation. Nanomedicine 13(13):1607-1621. PMID: 30028250.
  28. Pinaki S Nakod, Yonghyun Kim, Shreyas S Rao (2018) Biomimetic models to examine microenvironmental regulation of glioblastoma stem cells Cancer Letters 429:41-53. PMID: 29746930.
  29. Yibo Piao, Do Hyeong Gwon, Dong-Wook Kang, Tae Woong Hwang, Nara Shin, Hyeok Hee Kwon, Hyo Jung Shin, Yuhua Yin, Jwa-Jin Kim, Jinpyo Hong, Hyun-Woo Kim, Yonghyun Kim, Sang Ryong Kim, Sang-Ha Oh, Dong Woon Kim (2018) TLR4-mediated autophagic impairment contributes to neuropathic pain in chronic constriction injury mice. Molecular Brain 11(1):11. PMID: 29486776.
  30. Eun Hyun Ahn, Michael B Lee, Dong Joo Seo, Juseong Lee, Yonghyun Kim, Kshitiz Gupta (2018) Sphingosine induces apoptosis and down-regulation of MYCN in PAX3-FOXO1-positive alveolar rhabdomyosarcoma cells irrespective of TP53 mutation. Anticancer Research 38(1):71-76. PMID: 29277758.
  31. Ursula L Triantafillu, Jaron N Nix, Yonghyun Kim (2018) Novel fluid shear-based dissociation device for improved single cell dissociation of spheroids and cell aggregates. Biotechnology Progress 34(1):293-298. PMID: 28726331.

  32. 2017

  33. Justin W Magrath, Yonghyun Kim (2017) Salinomycin's potential to eliminate glioblastoma stem cells and treat glioblastoma multiforme. International Journal of Oncology 51(3):753-759. PMID: 28766685.
  34. Hyunjung Baek, Hyo Jung Shin, Jwa-Jin Kim, Nara Shin, Sena Kim, Min-Hee Yi, Enji Zhang, Jinpyo Hong, Joon Won Kang, Yonghyun Kim, Cuk-Seong Kim, Dong Woon Kim (2017) Primary cilia modulate TLR4-mediated inflammatory responses in hippocampal neurons. Journal of Neuroinflammation 14(1):189. PMID: 28927423.
  35. Fengrui Qu, Seungjo Park, Kristina Martinez, Jessica L Gray, Fathima Shazna Thowfeik, John A Lundeen, Ashley E Kuhn, David J Charboneau, Deidra L Gerlach, Molly M Lockart, James A Law, Katherine L Jernigan, Nicole Chambers, Matthias Zeller, Nicholas A Piro, W Scott Kassel, Russell H Schmehl, Jared J Paul, Edward J Merino, Yonghyun Kim, Elizabeth T Papish (2017) Ruthenium complexes are pH-activated metallo prodrugs (pHAMPs) with light-triggered selective toxicity toward cancer cells. Inorganic Chemistry 56(3):7519-7532. PMID: 28636344.
  36. Anisa S Qayyum, Era Jain, Grant Kolar, Yonghyun Kim, Scott A Sell, Silviya P Zustiak (2017) Design of electrohydrodynamic sprayed polyethylene glycol hydrogel microspheres for cell encapsulation. Biofabrication 9(2):025019. PMID: 28516893.
  37. Brandon J Hill, Yaolin Xu, Jennifer Sherwood, Andrew D Raddatz, Yonghyun Kim, Yuping Bao, Carol Duffy (2017) A coiled-coil strategy for the directional display of multiple proteins on the surface of iron oxide nanoparticles. RSC Advances 7(20):12133-12143.
  38. Ursula L Triantafillu, Seungjo Park, Nikki L Klaassen, Andrew D Raddatz, Yonghyun Kim (2017) Fluid shear stress induces cancer stem cell-like phenotype in MCF7 breast cancer cell line without inducing epithelial to mesenchymal transition. International Journal of Oncology 50(3):993-1001. PMID: 28197635.
  39. Sang Yeon Cho, Seon-Hwan Kim, Min-Hee Yi, Enji Zhang, Eunjee Kim, Jisoo Park, Eun-Kyeong Jo, Young Ho Lee, Min Soo Park, Yonghyun Kim, Jongsun Park, Dong Woon Kim (2017) Expression of PGC1α in glioblastoma multiforme patients. Oncology Letters 13(6):4055-4076. PMID: 28599408.
  40. Elizabeth M Haley, Samantha G Tilson, Ursula L Triantafillu, Justin W Magrath, Yonghyun Kim (2017) Acidic pH with coordinated reduction of basic fibroblast growth factor maintains the glioblastoma stem cell-like phenotype in vitro. Journal of Bioscience and Bioengineering 123(5):634–641. PMID: 28063758.

  41. 2016

  42. Min-Hee Yi, Enji Zhang, Jwa-Jin Kim, Hyunjung Baek, Nara Shin, Sena Kim, Sang Ryong Kim, Hang-Rae Kim, Sung Joong Lee, Jin Bong Park, Yonghyun Kim, O-Yu Kwon, Young Ho Lee, Sang-Ha Oh, Dong Woon Kim (2016) CD200R/Foxp3-mediated signalling regulates microglial activation. Scientific Reports 6:10. PMID: 27731341.
  43. Hyunjung Baek, Min-Hee Yi, Sudip Pandit, Jin Bong Park, Hyeok Hee Kwon, Enji Zhang, Sena Kim, Nara Shin, Eunjee Kim, Young Ho Lee, Yonghyun Kim, Dong Woon Kim, Joon Won Kang (2016) Altered expression of KCC2 in GABAergic interneuron contributes prenatal stress-induced epileptic spasms in infant rat. Neurochemistry International 97:57-64. PMID: 27180051.
  44. Daniel J Klionsky, et al (2016) Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy 12(1):1-222. PMID: 26799652.

  45. 2015

  46. Faride Ordikhani, Yonghyun Kim, Silviya P Zustiak (2015) The role of biomaterials on cancer stem cell enrichment and behavior. JOM 67(11):2543-2549.
  47. Samantha G Tilson, Elizabeth M Haley, Ursula L Triantafillu, David A Dozier, Catherine P Langford, G Yancey Gillespie, Yonghyun Kim (2015) ROCK inhibition facilitates in vitro expansion of glioblastoma stem-like cells. PLoS One 10(7):e0132823. PMID: 26167936.
  48. Enji Zhang, Min-Hee Yi, Nara Shin, Hyunjung Baek, Sena Kim, Eunjee Kim, Kisang Kwon, Sunyeul Lee, Hyun-Woo Kim, Yong Chul Bae, Yonghyun Kim, O-Yu Kwon, Won Hyung Lee, Dong Woon Kim (2015) Endoplasmic reticulum stress impairment in the spinal dorsal horn of a neuropathic pain model. Scientific Reports 5:11555. PMID: 26109318.

  49. 2014

  50. Nazrul Islam, Yonghyun Kim, Julia M Ross, Mark R Marten (2014) Proteomic analysis of Staphylococcus aureus biofilm cells grown under physiologically relevant fluid shear stress conditions. Proteome Science 12:21. PMID: 24855455.
  51. Elizabeth M Haley, Yonghyun Kim (2014) The role of basic fibroblast growth factor in glioblastoma multiforme and glioblastoma stem cells and in their in vitro culture. Cancer Letters 346(1):1-5. PMID: 24333730.

  52. 2013

  53. Wonyoung Kang, Ho Jun Seol, Dong-Ho Seong, Jandi Kim, Yonghyun Kim, Seung U Kim, Do-Hyun Nam, Kyeung Min Joo (2013) Adenosine potentiates the therapeutic effects of neural stem cells expressing cytosine deaminase against metastatic brain tumors. Oncology Reports 30(3):1101-1106. PMID: 23828015.
  54. Heekyoung Yang, Hye Won Lee, Yonghyun Kim, Yeri Lee, Yeon-Sook Choi, Kang Ho Kim, Juyoun Jin, Jeongwu Lee, Kyeung Min Joo, Do-Hyun Nam (2013) Radiosensitization of brain metastasis by targeting c-MET. Laboratory Investigation 93(3):344-353. PMID: 23381625.

  55. 2012

  56. Mi-Young Jo, Young Gyu Kim, Yonghyun Kim, Se Jeong Lee, Mi Hyun Kim, Kyeung Min Joo, Hyeon Ho Kim, Do-Hyun Nam (2012) Combined therapy of temozolomide and ZD6474 (vandetanib) effectively reduces glioblastoma tumor volume through anti-angiogenic and anti-proliferative mechanisms. Molecular Medicine Reports 6(1):88-92. PMID: 22505191.
  57. Yong Jung, Kyeung Min Joo, Dong Ho Seong, Yoon-La Choi, Doo-Sik Kong, Yonghyun Kim, Mi Hyun Kim, Juyoun Jin, Yeon-Lim Suh, Ho Jun Seol, Chul Soo Shin, Jung-Il Lee, Jong-Hyun Kim, Sang Yong Song, Do-Hyun Nam (2012) Identification of prognostic biomarkers for glioblastomas using protein expression profiling. International Journal of Oncology 40(4):1122-1132. PMID: 22179774.
  58. Daniel J Klionsky, et al (2012) Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 8(4):445-544. PMID: 22966490.
  59. Yonghyun Kim, Kang Ho Kim, Jeena Lee, Young-Ae Lee, Misuk Kim, Se Jeong Lee, Kernyu Park, Heekyoung Yang, Juyoun Jin, Kyeung Min Joo, Jeongwu Lee, Do-Hyun Nam (2012) Wnt activation is implicated in glioblastoma radioresistance. Laboratory Invesitgation 92(3):466-473. PMID: 22083670.
  60. Kyeung Min Joo, Juyoun Jin, Eunhee Kim, Kang Ho Kim, Yonghyun Kim, Bong Gu Kang, Youn-Jung Kang, Justin D Lathia, Kwang Ho Cheong, Paul H Song, Hyunggee Kim, Ho Jun Seol, Doo-Sik Kong, Jung-Il Lee, Jeremy N Rich, Jeongwu Lee, Do-Hyun Nam (2012) MET signaling regulates glioblastoma stem cells. Cancer Research 72(15):3828-3838. PMID: 22617325.

  61. 2011

  62. Juyoun Jin, Kyeung Min Joo, Se Jeong Lee, Mi-Young Jo, Yonghyun Kim, Younggeon Jin, Joong Kyu Kim, Ji Mi Ahn, Mi-Jung Yoon, Jaeseung Lim, Do-Hyun Nam (2011) Synergistic therapeutic effects of cytokine-induced killer cells and temozolomide against glioblastoma. Oncology Reports 25(1):33-39. PMID: 21109954.
  63. Se Jeong Lee, Yonghyun Kim, Mi-Young Jo, Hyeong-Seok Kim, Younggeon Jin, Seung U Kim, Juyoun Jin, Kyeung Min Joo, Do-Hyun Nam (2011) Combined treatment of tumor-tropic human neural stem cells containing the CD suicide gene effectively targets brain tumors provoking a mild immune response. Oncology Reports 25(1):63-68. PMID: 21109958.
  64. Yonghyun Kim, Nazrul Islam, Bill J Moss, M P Nandakumar, Mark R Marten (2011) Autophagy induced by rapamycin and carbon-starvation have distinct proteome profiles in Aspergillus nidulans. Biotechnology and Bioengineering 108(11):2705-2715. PMID: 21618477.
  65. Kang Ho Kim, Hae Yong Yoo, Kyeung Min Joo, Yong Jung, Juyoun Jin, Yonghyun Kim, Su Jin Yoon, Seung Ho Choi, Ho Jun Seol, Woong Yang Park, Do Hyun Nam (2011) Time-course analysis of DNA damage response-related genes after in vitro radiation in H460 and H1229 lung cancer cell lines. Experimental & Molecular Medicine 43(7):419-426. PMID: 21633183.
  66. Ho Jun Seol, Juyoun Jin, Dong-Ho Seong, Kyeung Min Joo, Wonyoung Kang, Heekyoung Yang, Jandi Kim, Chul Soo Shin, Yonghyun Kim, Kang Ho Kim, Doo-Sik Kong, Jung-Ii Lee, Karen S Aboody, Hong Jun Lee, Seung U Kim, Do-Hyun Nam (2011) Genetically engineered human neural stem cells with rabbit carboxyl esterase can target brain metastasis from breast cancer. Cancer Letters 311(2):152-159. PMID: 21868150.
  67. Juyoun Jin, Ki Hyun Bae, Heekyoung Yang, Se Jeong Lee, Hyein Kim, Yonghyun Kim, Kyeung Min Joo, Soo Won Seo, Tae Gwan Park, Do-Hyun Nam (2011) In vivo specific delivery of c-Met siRNA to glioblastoma using cationic solid lipid nanoparticles. Bioconjugate Chemistry 22(12):2568-2572. PMID: 22070554.
  68. Ho Jun Seol, Hae Yong Yoo, Juyoun Jin, Kyeung Min Joo, Hyeong-Seok Kim, Su Jin Yoon, Seung Ho Choi, Yonghyun Kim, Hong Ryull Pyo, Do-Hoon Lim, Wook Kim, Hong-Duck Um, Jong Hyun Kim, Jung-Ii Lee, Do-Hyun Nam (2011) The expression of DNA damage checkpoint proteins and prognostic implication in metastatic brain tumors. Oncology Research 19(8-9):381-390. PMID: 22329197.

  69. 2009

  70. Yonghyun Kim, Kyeung Min Joo, Juyoun Jin, Do-Hyun Nam (2009) Cancer stem cells and their mechanism of chemo-radiation resistance. International Journal of Stem Cells 2(2):109-114. PMID: 24855529.

  71. 2008

  72. Yonghyun Kim, M P Nandakumar, Mark R Marten (2008) The state of proteome profiling in the fungal genus Aspergillus. Briefings in Functional Genomics and Proteomics 7(2):87-94. PMID: 18187513.
  73. Bill J Moss, Yonghyun Kim, M P Nandakumar, Mark R Marten (2008) Quantifying metabolic activity of filamentous fungi using a colorimetric XTT assay. Biotechnology Progress 24(3):780-783. PMID: 18386938.

  74. 2007

  75. Yonghyun Kim, M P Nandakumar, Mark R Marten (2007) Proteome map of Aspergillus nidulans during osmoadaptation. Fungal Genetics and Biology 44(9):886-895. PMID: 17258477.
  76. Yonghyun Kim, M P Nandakumar, Mark R Marten (2007) Proteomics of filamentous fungi.  Trends in Biotechnology 25(9):395-400. PMID: 17681627.

  77. 2003

  78. Bernard Fried, Yonghyun Kim (2003) Effects of larval Echinostoma caproni and Schistosoma mansoni infection on the heart rate of Biomphalaria glabrata snails. The Veliger 46(2):182-183.

  79. 2002

  80. Bernard Fried, Robert Laterra, Yonghyun Kim (2002) Effects of exogenous glucose on survival and infectivity of Schistosoma mansoni cercariae. Korean Journal of Parasitology 40(1):55-58. PMID: 11954549.
  81. Bernard Fried, Robert LaTerra, Yonghyun Kim (2002) Emergence of cercariae of Echinostoma caproni and Schistosoma mansoni from Biomphalaria glabrata under different laboratory conditions. Journal of Helminthology 76(4):369-371.
  82. Yonghyun Kim, Bernard Fried, Joseph Sherma (2002) Thin layer chromatographic analysis of lutein and beta-carotene in Biomphalaria glabrata maintained on a high fat diet. The Veliger 45(3) 256-258.

  83. 2001

  84. Stacey D Wagner, Yonghyun Kim, Bernard Fried, Joseph Sherma (2001) Thin-layer chromatographic analysis of glucose, maltose, and raffinose in Biomphalaria glabrata (gastropoda) infected with Echinostoma caproni (trematoda). Journal of Planar Chromatography-Modern TLC 14(6):459-461.
  85. Yonghyun Kim, Bernard Fried, Joseph Sherma (2001) Thin-layer chromatographic analysis of carbohydrates in Biomphalaria glabrata snails maintained on a high-fat diet. Journal of Planar Chromatography-Modern TLC 14(1):61-63.
Last updated: 3-28-2023